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OpenTrials
Completed

NCT Number: NCT02689791

Effect of Resistant Wheat Starch on Subjective Appetite and Food Intake in Healthy Adults

A randomized, single-blind, cross-over study was conducted to determine the effect of replacing standard wheat flour (SWF) with resistant wheat starch (RWS) on markers of appetite and food intake in healthy adults.

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Key information

Conditions

Feeding Behavior Behavior Behavior, Animal

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI 18.5-29.9 kg/m2
  • Regular breakfast consumers (>5 days/week)

Exclusion criteria

  • not weight stable (?3 kg weight change in previous 3 months)
  • use/used tobacco products
  • presence of acute or chronic illness
  • restrained eater (>13 on the restraint section of the three-factor eating questionnaire)

Treatment and study plan

Resistant Starch Type 4

Dietary Supplement

single dose 26g fiber given at the breakfast meal

Other names: Fibersym

Primary outcomes

  1. Caloric intake

    Time frame: Single Day

    calories consumed at post-treatment lunch meal and total calories consumed on the treatment day

Secondary outcomes

  1. Visual analogue scale measures of subjective appetite

    Time frame: Single Day

    0-100mm scale to assess hunger, fullness, thirst, desire to eat and prospective consumption

  2. Serum concentrations of biomarkers of appetite

    Time frame: 150 minutes

    CCK, ghrelin, PYY3-36 and GLP-1

  3. Plasma concentrations of biomarkers of glycemic response

    Time frame: 150 minutes

    Glucose, Insulin, GLP-1

Interested in participating?

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Sponsors and collaborators

Lead sponsor

Iowa State University

Other

Registry information

Important dates

Study start
2012
Primary completion
2013
Study completion
2014
First posted
Feb 24, 2016
Registry last updated
Feb 24, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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