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OpenTrials
Completed

NCT Number: NCT02528578

Modulation of Painful Perception

The objective of the study is to evaluate in healthy volunteers, the influence of empathy on pain perception.

It is widely accepted in the clinical management that the feeling of listening to the patients' pain would have a favorable influence on the pain, and conversely, the lack of listening would be aggravating.

In this study, the volunteer will receive painful thermal stimuli in empathetic context (l, empathetic or non-empathetic) Two situations will oppose, one where the examiner neglect or minimize the suffering of the voluntary and the other or the contrary, the subject will receive empathy.

The first part of the project is to verify that the pain is influenced by the empathetic context. The second part will be conducted functional MRI, which should isolate the brain regions affected by other people's empathy for pain.

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Key information

Conditions

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hospices Civils de LYON, Lyon, France

Loading trial locations.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Right handed

Exclusion criteria

  • Pregnant or lactating women,
  • Against-indications to MRI
  • Drug intake of less than 12 hours,
  • Neurological history or deficits, psychiatric, auditory or visual.
  • Decline to participate

Treatment and study plan

thermal stimulation delivered by a thermode.

Device

Empathetic context (neutral, empathetic, non-empathetic) when thermal stimulation

Functional MRI

Other

MRI realised with thermal stimulations and empathetic context (neutral, empathetic, non-empathetic) when thermal stimulation

Primary outcomes

  1. Intensity of the perceived pain assessed by the volunteer by a analog scale (VAS) at each thermal stimulation.

    Time frame: Day 0

Secondary outcomes

  1. blood-oxygen-level dependent (MRI)

    Time frame: Day 0

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Saint Etienne

Other

Registry information

Acronym: MODOU

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Aug 19, 2015
Registry last updated
Sep 26, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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