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Completed

NCT Number: NCT02358954

Vestibular Pain Interactions

The goal is to establish the practical usefulness of vestibular stimulation for modulating pain perception and to describe the possible mechanisms that could underlie neural vestibular-somatosensory interactions.

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Key information

Conditions

Healthy

Age range

18 year–60 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

University hospital Zurich

Zurich, Canton of Zurich, CH-8091, Switzerland

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Weight: 50 - 100 kg
  • Height: 155 - 185 cm
  • Male subjects 18 years to 60 years of age
  • Sufficient command of German language
  • Written informed consent by the participant after information about the project
  • Without any known history of neurological disease (especially motor, somatosensory disorders, peripheral neuropathies).
  • Right-handedness

Exclusion criteria

  • Intellectually or mental impaired subjects
  • Drug abuse
  • Chronic alcohol consumption
  • No use of marihuana 24h before measurements.
  • No history of vestibular or auditory disorders.
  • Diabetes mellitus
  • Participants of other studies during study period and 30 days prior to study begin
  • Any regular concomitant medication
  • Abnormal QST parameters at the baseline measurement.
  • Absent CHEPs-Potentials at the baseline measurement.

Treatment and study plan

Quantitative sensory testing

Procedure

Measurement of warm and cold detection and pain thresholds

Other names: QST

CHEPS

Procedure

Measurement of amplitude and latency of cortically evoked potentials

Other names: Contact heat evoked potentials

3D Turntable

Procedure

Vection stimulation

Procedure

Primary outcomes

  1. Pain thresholds

    Time frame: After study inclusion, Day1

    The change in heat or cold pain threshold after physical vestibular stimulation and vection stimulation

Sponsors and collaborators

Lead sponsor

University of Zurich

Other

Registry information

Official study title

Modulation of Pain Responses by Vestibular Stimulation. A Contact Heat Evoked Potential Study.

Acronym: VPI

Important dates

Study start
2015
Primary completion
2015
Study completion
2015
First posted
Feb 9, 2015
Registry last updated
Jul 14, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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