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OpenTrials
Completed

NCT Number: NCT01948674

Cognitive Stimulation in Adolescents

The purpose of this study is to see if computer tasks that challenge the brain (cognitively stimulating tasks) can improve memory and other types of thinking in adolescents and young adults who are being treated for substance use problems. The study will compare the effects of different versions of the computer tasks.

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Key information

Conditions

Substance Use Disorders Chemically-Induced Disorders Mental Disorders Substance-Related Disorders

Age range

14 year–21 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Mountain Manor Treatment Center

Baltimore, Maryland, 21229, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age 14-21
  • Diagnosis of substance use disorder (SUD) by DSM-IV criteria with marijuana as primary substance of abuse
  • eligible for intensive outpatient treatment

Exclusion criteria

  • Untreated psychiatric disorder that might make participation hazardous
  • Any condition associated with severe cognitive impairment

Treatment and study plan

Computerized tasks

Behavioral

The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks.

Primary outcomes

  1. working memory (change from baseline)

    Time frame: expected within 2 weeks after intervention

Secondary outcomes

  1. timeline follow back (change from baseline)

    Time frame: expected within 2 weeks after intervention

  2. delay discounting (change from baseline)

    Time frame: expected within 2 weeks after intervention

  3. Stroop (change from baseline)

    Time frame: expected within 2 weeks after intervention

  4. reading comprehension (change from baseline)

    Time frame: expected within 2 weeks after intervention

  5. emotion regulation (change from baseline)

    Time frame: expected within 2 weeks after intervention

  6. Go-No Go (change from baseline)

    Time frame: expected within 2 weeks after intervention

  7. Global Appraisal of Individual Needs (change from baseline)

    Time frame: expected within 2 weeks after intervention

Sponsors and collaborators

Lead sponsor

Johns Hopkins University

Other

Collaborators

  • National Institute on Drug Abuse (NIDA)

Registry information

Official study title

Cognitive Training in Adolescents During Treatment for Substance Use Disorders

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Sep 23, 2013
Registry last updated
Aug 24, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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