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Completed

NCT Number: NCT01841710

Genetic Variability in Taste Perception

This proposal describes a pilot study aimed at determining whether genetic variations in taste receptors determine differential taste tolerability of pediatric medications.

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Key information

Conditions

Healthy

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Monell Chemical Senses Center

Philadelphia, Pennsylvania, 19104, United States

About this study

This is a cross-sectional call-back study of taste perception and the relationship between taste perception and taste receptor genotype.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult females who were previously enrolled in Efficacy of Bitter Blockers on Taste Acceptance in Pediatric Populations Study (Protocol #809789)

Exclusion criteria

  • Women who are pregnant
  • Women on drugs with potential serious adverse effects that are mediated through cytochrome P450.

Treatment and study plan

Primary outcomes

  1. Psychophysical data for taste solutions

    Time frame: 1-2 hours

    Primary outcome variables are intensity ratings of pediatric medications as well as a variety of generally recognized as safe bitter and non-bitter compounds.

Secondary outcomes

  1. Maternal practices and perceptions of medication use

    Time frame: 1-2 hours

    Secondary outcome variables include questions related to maternal practices and perceptions of medication use and compliance of their children.

Sponsors and collaborators

Lead sponsor

Monell Chemical Senses Center

Other

Collaborators

  • Children's Hospital of Philadelphia
  • National Institute on Deafness and Other Communication Disorders (NIDCD)
  • University of Pennsylvania

Registry information

Important dates

Study start
2012
Primary completion
2015
Study completion
2015
First posted
Apr 26, 2013
Registry last updated
Mar 16, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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