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NCT Number: NCT01771718

Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy

The purpose of this pilot study is to employ multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin lesions for characterization of their morphologic and functional features.

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Key information

Conditions

Skin Lesion

Sex eligibility

All sexes

Study type

Observational

Primary location

Beckman Laser Institute Medical Clinic

Irvine, California, 92612, United States

Location status: Recruiting

About this study

This study is performed using a multiphoton microscopy-based tomograph (MPTflex) developed by JenLab, GmbH (Germany) and a MPM imaging system developed at BLI: Fast Large Area Multiphoton Exoscope (FLAME) to image non-invasively normal and lesional skin. Skin lesions are imaged by multiphoton microscopy and images are compared to those obtained from histopathology through standard of care processed skin biopsies.

Any biopsies will be performed by the health care provider as a standard of care procedure.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male or Female all age groups
  • Ability to understand and carry out subject instructions

Exclusion criteria

  • Pregnant women

Treatment and study plan

Multiphoton microscopy-based tomograph.

Device

non-invasive optical biopsy

Primary outcomes

  1. high-resolution images of skin

    Time frame: up to 12 months

    The complementary imaging modalities (MPM, MI) will provide insights into a better understanding of the relationship between microscopic and macroscopic properties of the skin.

Interested in participating?

Recruiting

Interested in participating?

Request Info

Sponsors and collaborators

Lead sponsor

University of California, Irvine

Other

Collaborators

  • National Institute for Biomedical Imaging and Bioengineering (NIBIB)

Registry information

Official study title

Non-invasive Skin Imaging Using Multiphoton Microscopy

Important dates

Study start
2012
Primary completion
2028
Study completion
2028
First posted
Jan 18, 2013
Registry last updated
Aug 31, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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