MR-Guided Cryoablation of Prostate Bed Recurrences

The purpose of this research is to see if MR-guided cryoablation can effectively treat prostate tumor recurrences.

Active, not recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Prostate Tumors Genital Diseases Genital Diseases, Male Genital Neoplasms, Male Male Urogenital Diseases Neoplasms Neoplasms by Site Prostatic Diseases Prostatic Neoplasms Urogenital Diseases Urogenital Neoplasms

Age range

30 year–100 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with "biopsy proven" soft tissue tumor recurrences of prostate fossa
Surgery is not a desirable alternative therapy at the time of enrollment
Radiation therapy has failed or not indicated or can be safely postponed
Tumor size is < 5 cm at its largest diameter
Tumor does not encompass the rectal wall or external urethral sphincter
Patient is able to undergo MRI

Exclusion criteria

Treatment and study plan

MR-guided cryoablation

Procedure

Primary outcomes

Evaluation of target lesion at 3-6, 12, 24, and 36 month imaging follow-up

Time frame: 3 years

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Official study title

Technical Success, Safety, and Short and Long-term Efficacy for MR-Guided Cryoablation of Prostate Bed Recurrences

Important dates

Study start: 2012
Primary completion: 2026
Study completion: 2026
First posted: Nov 15, 2012
Registry last updated: Sep 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Active, not recruiting