Effect of Nefopam on Acute Postoperative Pain in Patients Undergoing Orthognathic Surgery

The aim of this study is to determine the analgesic effect of perioperative nefopam on acute pain in patient undergoing orthognathic surgery.

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Key information

Conditions

Pain Neurologic Manifestations Orthognathic Surgery Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Seoul St.Mary's Hospital

Seoul, Seocho-gu, 137-701, South Korea

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

aged 20-60 years
undergoing elective orthognathic surgery

Exclusion criteria

pregnancy
psychiatric disease
hepatobiliary or renal disease
monoamine oxidase inhibitor-taking patients

Treatment and study plan

Nefopam

Drug

nefopam infusion for postoperative 24 hours

normal saline (control)

Drug

normal saline infusion for postoperative 24 hours

Primary outcomes

pain score on the visual analogue scale

Time frame: after orthognathic surgery (up to postoperative 24 hours)

Sponsors and collaborators

Lead sponsor

The Catholic University of Korea

Other

Registry information

Important dates

Study start: 2011
Primary completion: 2012
Study completion: 2012
First posted: Oct 27, 2011
Registry last updated: Feb 4, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed