Impact on Cognitive Function and Quality of Life of Adjuvant Chemotherapy in Patients Aged Over 65 Years: Application to Breast Cancer or Colon

Inclusion criteria

for patients with chemotherapy :

• Patient(e) aged over 65 years
• Non metastatic breast cancer
• Adjuvant chemotherapy Breast cancer: FEC, including Docetaxel Protocols
• No major cognitive impairment
• Lack of personality disorders and psychiatric disorders evolutionary
• Having signed the informed consent of study participation

Inclusion criteria

for patients without chemotherapy (control group):

• Patient(e) aged over 65 years
• Breast cancer
• Patients receiving no adjuvant chemotherapy
• No major cognitive impairment
• Lack of personality disorders and psychiatric disorders evolutionary
• Having signed the informed consent of study participation
• Matching on age, sex, cultural level and tumor location

Exclusion criteria

for patients with chemotherapy :

• Metastatic
• Cancer primitive other than breast
• Patients under 65 years
• Patients with adjuvant chemotherapy is associated with targeted therapy
• Patients who have received other cancer treatments (chemotherapy or radiotherapy brain)
• disorders of higher functions existing in the administration of chemotherapy
• Pathology psychiatric evolutionary
• Refusal of participation
• Patients unable to meet the cognitive tests
• Drug use
• Heavy drinking