Compare Effect of Surgical Antiseptic Preparations on Incise Drape Adhesion to Skin

Adhesive incise drapes are often used to provide a physical sterile barrier between the surrounding skin and the open wound at the beginning of a surgery. This study sought to determine the effect of presurgical skin antiseptic preparation on the adhesion of various incise drapes to the skin.

Inclusion criteria

• Subject is willing to sign the Research Consent form
• Healthy male or female subjects ages between 18 - 65
• Subject has agreed to be and appears to be compliant with requirements of the study
• Subject has a back (the product application site) of sufficient size, free of blemishes to comfortably fit 18 strips of 1/2" x 3" drape samples
• Subject is willing to have the back clipped or shaved if it has excessive hair

Exclusion criteria

• Sensitivity/allergy to adhesive products (e.g. medical tapes)
• Sensitivity to the antimicrobial agent iodine, povidone iodine (PVPI), isopropyl alcohol (IPA), or chlorhexidine gluconate (CHG)
• Allergy to seafood
• History of psoriasis dermatitis, or any skin condition that might be exacerbated by the action of removing adhesive materials
• Active dermatitis (rash), sunburn, blemishes, broken skin, cuts, and/or infection on the subject's back
• History of diabetes
• Subject is currently pregnant or thinks she may be pregnant or is nursing
• Subject is receiving steroid-based anti-inflammatory or immunosuppressant drug therapy
• Subject is taking antihistamine medication
• Subject has been using moisturizers or other skin contact materials on the test sites for 24 hours prior to the start of the study
• Subject has a back problem that prohibits him or her from lying face downward for approximately 2 hours