Effects of a Probiotic on Body Weight

Inclusion criteria

• Age: between 18 and 55 years old
• Weight: 30.0 kg/m2 ≤ BMI ≤ 39.9 kg/m2
• Non smokers
• Good general health
• A 2 weeks probiotics washout period prior to treatment initiation

Exclusion criteria

• Under antibiotics or treatments (medication or nutritional program) affecting body weight or glucose control for the last 3 months
• Currently participating or having participated in another clinical trial during the last 6 months prior to the beginning of this study
• Pregnant women, women who have given birth in the past year, women planning pregnancy in the next 6 months or menopausal women
• Excessive consumption of products enriched in probiotics (> 4 servings per week).
• History of drug or alcohol (> 2 drinks daily) abuse
• Abnormal thyroid hormone levels
• Intake of medication that could affect body weight and/or energy expenditure
• Family history of type 2 diabetes in first degree relatives
• Allergy to the ingredients in the study product and placebo
• Participant with anaemia
• Participant with a recent history of large weight fluctuations (e.g., > 10 kg in the past year
• Immune-compromised conditions
• Participant experiencing nausea, fever, vomiting, bloody diarrhoea or severe abdominal pain
• Participant with co-morbidity associated with obesity:

• Hypertension (≥ 140/90 mm Hg)
• Current use of antihypertensive medications, depression
• Prediabetes (fasting glucose >100mg/dL)
• Family history of premature coronary artery disease
• LDL > 2.0 mmol/L
• HDL < 1.3 mmol/L
• Smoking
• Obstructive sleep apnea
• Type 2 diabetes
• Cardiovascular disease.