Antimicrobial Pulpotomy of Primary Molars

There is a lack of evidence of the long-term successful outcomes of antimicrobial endodontic treatment for primary teeth. This study intended to evaluate (by survival analysis) the effectiveness of an antimicrobial pulpotomy (chloramphenicol, tetracycline, zinc oxide/eugenol) in primary molars compared to calcium hydroxide pulpectomy, testing the hypothesis that antimicrobial pulpotomy could be an alternative pulp therapy for primary teeth with pulp inflammation or necrosis.

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Key information

Conditions

Inflammation Necrosis Pathologic Processes Pathological Conditions, Signs and Symptoms

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Dental School

Goiânia, Goiás, 74605220, Brazil

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Healthy children (ASA PS 1)
Children presenting one or more primary molar with pulp inflammation or necrosis due to carious lesion and indicated for endodontic therapy

Exclusion criteria

Lost to follow-up

Treatment and study plan

Antimicrobial pulpotomy

Procedure

Pulpotomy of inflamed or necrotic pulp using an antimicrobial paste (chloramphenicol, tetracycline, zinc oxide/eugenol)as medication.

Other names: Antibacterial pulp therapy, Antibacterial pulpotomy, Non-vital pulpotomy

Calcium hydroxide pulpectomy

Procedure

Pulpectomy of inflamed or necrotic pulp using a calcium hydroxide paste as medication

Sponsors and collaborators

Lead sponsor

Universidade Federal de Goias

Other

Registry information

Official study title

Survival of Primary Molars Treated With Antimicrobial Pulpotomy or Calcium Hydroxide Pulpectomy

Important dates

Study start: 2000
Study completion: 2006
First posted: Nov 10, 2009
Registry last updated: Nov 10, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed