Rationales for Wound Care Management in Old World Cutaneous Leishmaniasis Patients

Inclusion criteria

• Present a suspected Old World Cutaneous Leishmaniasis lesion confirmed by Giemsa stained wound smears with no other skin diseases or infections and who
• Have never been previously treated with antimonial injections or any other form of anti-leishmanial medication.

Exclusion criteria

• Patients with more than one lesion are excluded.
• Patients with a lesion age of > 3 months are also excluded. The experience of the Kabul trial shows that patients presenting themselves for the first time with a lesion, which is older than three months, have either been pre-treated somewhere else and/or show a poor compliance during the trial.
• Patients below 12 years of age have to be excluded from the trial, because they cannot fill in the EQ-5D and Skindex questionnaire part of the health economic evaluation.
• Intralesional antimony injections are too painful for lesions located on the nose, lips or eyes. Therefore, patients presenting these lesions are excluded from the trial.
• For compliance reasons addicted patients and patients not available for follow-up are exclude from the trial.
• Patients with major uncontrolled diseases as tuberculosis, diabetes or HIV are excluded from the trial, since their management requires additional co-medications, which may affect wound healing.