Skip to main content
OpenTrials
Completed

NCT Number: NCT00947323

Simvastatin for Treating Erectile Dysfunction

This is a randomized clinical trial, double-blind, placebo controlled, to verify if simvastatin can improve erectile dysfunction in men with endothelial dysfunction, without any cardiac disease.It is hypothesized that the simvastatin can improve the endothelial function, improving the nitric oxide liberation in corpora cavernosa of the penis, resulting in improvement of erection.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Erectile Dysfunction C Reactive Protein Genital Diseases Genital Diseases, Male Male Urogenital Diseases Mental Disorders Sexual Dysfunction, Physiological Sexual Dysfunctions, Psychological Urogenital Diseases Vascular Disease Detected

Age range

35 year–70 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 3

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Erectile dysfunction
  • Elevated C reactive protein
  • Able to adhere the protocol

Exclusion criteria

  • Diabetes mellitus
  • Cardiac disease
  • Cerebral vascular disease
  • Hypogonadism
  • Any contraindication to simvastatin

Treatment and study plan

simvastatin

Drug

simvastatin 20 daily for six months.

Placebo

Drug

Primary outcomes

  1. Penile erection

Sponsors and collaborators

Lead sponsor

Santa Casa de Porto Alegre

Other

Registry information

Official study title

The Effect of Simvastatin in the Penile Erection: a Randomized, Double-blind Clinical Trial

Acronym: STED

Important dates

Study start
2006
Primary completion
2008
Study completion
2008
First posted
Jul 28, 2009
Registry last updated
Sep 27, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.