Study Evaluating Single Doses of ILV-095 in Healthy Subjects

Inclusion criteria

• Healthy men and women of non-childbearing potential ages 18 to 50 years old.
• Body mass index (BMI) in the range of 18 to 32 kg/m2 and body weight greater than or equal to50 kg.
• Healthy as determined by the investigator on the basis of screening evaluations.
• Nonsmoker or smoker of fewer than 10 cigarettes per day as determined by history. Must be able to abstain from smoking during the inpatient stay.
• Have a high probability for compliance with and completion of the study.

Exclusion criteria

• Presence or history of any disorder that may prevent the successful completion of the study.
• Any subject who had orthopedic surgery within 12 weeks of the screening visit or has planned (elective) orthopedic surgery within 12 weeks of study drug administration.
• Acute disease state (eg, nausea, vomiting, fever, active infection, or diarrhea) within 7 days before enrollment.