Interest of the Induction With Target-controlled Inhalation of Sevoflurane on Spikes Wave Occurrence

Sevoflurane is widely used for induction of anaesthesia. Several studies showed EEG abnormalities during mask induction with sevoflurane. The aim of our study was to test the induction target concentration of sevoflurane on the spikes wave occurrence.

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Key information

Conditions

General Anesthesia

Age range

18 year–60 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

CHU de Bordeaux

Bordeaux, 33000, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

programmed gynecological surgery
ASA 1 or 2

Exclusion criteria

arterial hypertension
gastro-oesophageal reflux
pregnancy
diabetes
obesity
asthma
tobacco

Treatment and study plan

Induction with Sevoflurane

Drug

Primary outcomes

Incidence of spike wave

Time frame: during anaesthesia induction with sevoflurane

Interested in participating?

Completed

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Sponsors and collaborators

Lead sponsor

University Hospital, Bordeaux

Other

Registry information

Acronym: SIZE

Important dates

Study start: 2006
Primary completion: 2008
Study completion: 2008
First posted: Oct 20, 2008
Registry last updated: Jun 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed