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OpenTrials
Completed

NCT Number: NCT00771940

Peripheral Metabolic Effects of Ghrelin

The aim of this study is to investigate putative peripheral effects of ghrelin on glucose and lipid metabolism in healthy men. Eight subjects will be enrolled. The hypothesis is that ghrelin infusion causes insulin resistance and lipolysis.

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Key information

Conditions

Healthy Controls

Age range

18 year–60 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 1

Primary location

Aarhus University Hospital

Aarhus, Dk-8000, Denmark

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI < 27 kg/m2
  • Written informed consent
  • Non-smoker

Exclusion criteria

  • Any disease including epilepsy
  • Any use of medications (excl. paracetamol)
  • Present or previous malignancy
  • Alcohol dependency
  • Allergy to any trial medication

Treatment and study plan

Ghrelin

Drug

Solvent, cont. infusion

Primary outcomes

  1. Plasma levels of glucose

    Time frame: During study day

Secondary outcomes

  1. Insulin signaling

    Time frame: Study day

  2. Serum levels of fatty acids

    Time frame: Study day

Interested in participating?

Completed

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Sponsors and collaborators

Lead sponsor

University of Aarhus

Other

Registry information

Official study title

Peripheral Metabolic Effects of Intra Arterial Ghrelin Infusion in Healthy Controls

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
Oct 15, 2008
Registry last updated
Feb 3, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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