Continuous and Discontinuous Determination of Propofol Concentration in Breathing Gas

This study should compare the propofol concentration in breathing gas and in plasma (before and) after lung passage. Propofol concentrations in breathing gas are continuously measured by a sensor. For comparison a discontinuous method is used. Neurophysiologic parameters for determination of depth of anesthesia are compared to the continuous measured propofol concentration in breathing gas.

Study hypothesis: continuous measured propofol concentration in breathing gas correlates to propofol concentration in plasma and depth of anaesthesia.

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Key information

Conditions

General Anesthesia

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Dept. of Anesthesiology , UK-SH, Campus Luebeck, Lübeck, Schleswig-Holstein, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patient destined for general anesthesia

Exclusion criteria

Heart insufficiency NYHA IV
Allergy to propofol

Interested in participating?

Completed

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Sponsors and collaborators

Lead sponsor

University of Luebeck

Other

Registry information

Official study title

Continuous and Discontinuous Determination of Propofol Concentration in Breathing Gas - Compared With Propofol Concentration in Plasma (Before and) After Lung Passage and Neurophysiological Parameters

Important dates

Study start: 2007
Study completion: 2010
First posted: Sep 20, 2007
Registry last updated: Oct 30, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed