NCT Number: NCT00482638
Study of Safety, Tolerability and Efficacy of MK0493 in Obese Patients (0493-008)(COMPLETED)
To assess the effect of MK0493 on body weight, blood pressure, mood, and appetite.
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Notify MeKey information
Conditions
Age range
21 year–65 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Phase 2
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Patient is between 21 and 65 years
- Patient is able to read and understand and complete study questionnaires
- Patient is not pregnant or breast-feeding and does not plan to become pregnant for the duration of the study and post-study follow-up period
Exclusion criteria
- Patient has a history of significant psychiatric disorder (such as major depression, bipolar disorder, bulimia, or anorexia nervosa
- Patient is HIV positive as determined by medical history
- Patient has undergone surgical treatment for obesity
- Patient plans to consume more than two 8 ounce glasses of grapefruit juice per day during the study
- Patient participated in another clinical study involving an investigational drug) within 3 months prior to Visit 1
- Patient is currently a heavy consumer of alcohol (>2 drinks per day or >14 drinks per week [1 drink is defined as 2 oz hard alcohol, 5 oz wine, 12 oz beer], or uses (including recreational use) any illicit drugs, or has a history of drug or alcohol abuse
Treatment and study plan
Sponsors and collaborators
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Registry information
Important dates
- Study start
- 2004
- Primary completion
- 2004
- Study completion
- 2004
- First posted
- Jun 5, 2007
- Registry last updated
- Nov 14, 2019
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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