Six Months DHEA Treatment in Female Adrenal Failure

DHEA is an adrenal deriven androgen precourser. The impact of DHEA substitution therapy in adrenal failure is unknown as well as the physiologically effects of DHEA is unknown. Effects of physiologically DHEA substitution is investigated in the model of female adrenal failure.

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Key information

Conditions

Adrenal Insufficiency Adrenal Gland Diseases Endocrine System Diseases

Age range

18 year–60 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Female,
Adrenal insuficiency,
Stable and safe anticonception,
Stable hydrocortison substituation treatment.

Exclusion criteria

Neoplastic and thromboembolic disease,
Diabetes mellitus.

Treatment and study plan

Dehydroepiandrosterone (DHEA)

Drug

Primary outcomes

Quality of life parameteres, cardiovascular parameters, bodycomposition, exercise parameters, hormonal and serological parameters, fuel metabolisme.

Time frame: six months

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Completed

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Sponsors and collaborators

Lead sponsor

University of Aarhus

Other

Registry information

Official study title

Physiolocal Effects of 6 Months DHEA Substitutional Therapy in Female Adrenal Failure in a Randomised, Placebo Controlled and Overcrossed Study.

Important dates

Study start: 2001
Study completion: 2003
First posted: May 10, 2007
Registry last updated: May 10, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed