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OpenTrials
Completed

NCT Number: NCT00145028

Determination of Carboplatin's Optimal Plasmatic Exposure

To determine Carboplatin's optimal exposures(optimal AUCs)and parameters they depend on.

Completed

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Key information

Conditions

Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Centre Paul Papin, Angers, France

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Carcinoma histologically proved and which must be treated by Carboplatin, excepted weekly administered Carboplatin treatments
  • Age > 18 years
  • Neutrophils > 1500/mm3, blood-platelets > 100000/mm3
  • Patient with intravenous administration route for chemotherapy independent of the one used for blood samples ( for Investigators centers achieving pharmacokinetic examination)
  • Well-informed written consent, signed by the patient

Exclusion criteria

  • Carboplatin treatment's contra-indication
  • Patient with clinically detectable cerebral metastasis
  • Pregnant or nursing women
  • Patient under guardianship or trusteeship
  • Patient whose venous status don't permit a peripheral intravenous administration route's placing (for Investigators centers achieving pharmacokinetic examination)

Treatment and study plan

carboplatin

Drug

Primary outcomes

  1. To determine Carboplatin's optimal exposures (optimal AUCs) and parameters they depend on.

Secondary outcomes

  1. To assign a standardization method for Carboplatin doses's calculation in chemotherapy's protocol including this drug.

Sponsors and collaborators

Lead sponsor

Institut Claudius Regaud

Other

Registry information

Important dates

Study start
2005
Primary completion
2007
Study completion
2009
First posted
Sep 5, 2005
Registry last updated
Sep 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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