99th Percentile Upper Reference Limit (URL) for the Meritas Troponin I Test

Prospective multicenter sample collection and testing study. Approximately 750 apparently healthy subjects, including healthy subjects with stable co-morbidities, age, gender and ethnicity dispersed will be eligible for enrollment

Inclusion criteria

• Male or female at least 21 years of age at the time of enrollment in the study.
• Subjects with no medications or no changes in their medications in the last 3 months.
• Subjects with and without chronic stable morbidities (i.e., renal insufficiency, hypertension, diabetes, hypercholesterolemia, pulmonary disorders, coronary disease, musculoskeletal disorders, etc.).
• Subjects able to understand and sign the informed consent and the patient questionnaire.

Exclusion criteria

• Subjects with a history of heart failure and/or, having received treatment for heart failure.
• Subject with renal failure.
• Subjects with a history of unstable heart disease or angina complaints.
• Subjects with any change in their medication in the last 3 months (diabetics may have small variations in glucose medications but may not have unstable disease, or have suffered a diabetic crisis in the last 6 months).
• Any known acute infection in the last 30 days.
• Marathon runners or extreme athletes.
• Pregnant (self-reported).