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Completed

NCT Number: NCT02873143

5 Year Follow-up of Adolescents With Knee Pain

The prevalence of adolescent knee pain is 33%, and patellofemoral pain (PFP) is the most common diagnosis with a nontraumatic onset. The 5-year prognosis of adolescent PFP compared with other types of knee pain is unknown.

In 2011, a cohort of 2200 adolescents aged 15 to 19 years answered an online questionnaire on musculoskeletal pain. Of these, 504 reported knee pain, and 153 of these were clinically diagnosed with PFP. Now, after 5 years, the 504 adolescents, as well as 252 randomly selected adolescents who did not report knee pain in 2011, will be contacted again to gain insights into their prognosis.

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Key information

Conditions

Patellofemoral Pain Syndrome Joint Diseases Knee Pain Musculoskeletal Diseases

Age range

15 year–19 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

From the 504, 153 were diagnosed with PFP, the criteria for which included:

  • insidious onset of anterior knee or retropatellar pain for longer than 6 weeks that was provoked by at least 2 of the following: prolonged sitting or kneeling, squatting, running, hopping, or stair climbing; tenderness on palpation of the patella; pain when stepping down; or double-leg squatting.

Exclusion criteria

were:

  • concomitant injury or pain from the hip, lumbar spine, or other knee structures
  • self-reported patellofemoral instability
  • knee joint effusion.

Treatment and study plan

No intervention

Other

No intervention

Primary outcomes

  1. Knee pain during the last week

    Time frame: 5 years

    All subjects are asked if they experienced knee pain during the last week

Secondary outcomes

  1. Knee pain during the last 30 days

    Time frame: 5 years

    Did you experience knee pain during the last 30 days?

  2. Frequency of knee pain

    Time frame: 5 years

    Frequency of knee pain divided into (almost daily, several times per week, weekly, monthly, rarely, never

  3. When did your knee pain resolve

    Time frame: 5 years

  4. Pain in other regions of the body

    Time frame: 5 years

  5. Seeking medical attention for your knee pain

    Time frame: 5 years

  6. Previous treatments for your knee pain

    Time frame: 5 year

  7. Use of pain medication

    Time frame: 5 years

  8. Worst pain last week

    Time frame: 5 years

    Measured on a numeric rating scale

  9. Knee Injury and Osteoarthritis Outcome score

    Time frame: 5 years

  10. Health-related quality of life

    Time frame: 5 years

    Measure with the EQ-5D-3L

  11. The influence of knee pain on choice of activity level, mood, choice of education and professional career

    Time frame: 5 years

  12. Physical activity level

    Time frame: 5 years

    Measured with the IPAQ

  13. Number of sports participation per week

    Time frame: 5 years

  14. The effect of knee pain on sports participation

    Time frame: 5 years

  15. Self-reported sleep problems

    Time frame: 5 years

    Assessed by asking three questions related to: trouble falling asleep, wake several times per night and trouble staying asleep.

Sponsors and collaborators

Lead sponsor

Aalborg University

Other

Collaborators

  • Copenhagen University Hospital, Denmark
  • Research Unit for General Practice in Aalborg
  • University of Southern Denmark

Registry information

Official study title

5 Year Follow-up of Adolescents With Knee Pain - a Prospective Cohort Study of 504 Adolescents

Important dates

Study start
2016
Primary completion
2016
Study completion
2017
First posted
Aug 19, 2016
Registry last updated
Jan 27, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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