3D Analysis of Cemento-Osseous Lesions | Clinical Trial

Key information

Conditions

Bone Diseases Cone-Beam Computed Tomography Florid Cemento-osseous Dysplasia Musculoskeletal Diseases

Study type

Observational

Primary location

Recep Tayyip Erdogan University Training and Research Hospital

Rize, 53100, Turkey (Türkiye)

About this study

Fibro-osseous lesions of the jaws are one of the important lesion groups for which identification and diagnosis create clinical difficulties. In previous studies, the features of the lesions and the effects of COD on anatomical structures were analysed via CBCT images by measuring the lesion's dimensions linearly for the first time in the Brazilian population. However, 3D measurements of the volume need to be taken to assess the actual spread over adjacent anatomical structures. The purpose of this retrospective study is to measure the volume of the lesions that have been diagnosed as COD in the Turkish population by using 3D images. This will contribute to an advanced study conducted on the global population to observe a change in these morphologies with respect to different geographical and ethnic origins.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

They were diagnosed with fibro-osseous lesions with the help of cone beam computed tomography between 2017 and 2020 were included in the study.
The lesions diagnosed radiologically and followed up for at least one year were included in this study.

Exclusion criteria

-Radiographs with insufficient diagnostic images were not included.

Treatment and study plan

The data of patients who had applied to the clinic for various reasons and were diagnosed with fibro-osseous lesions

Other

lesions diagnosed radiologically and followed up for at least one year were included in this study with the help of cone beam computed tomography.

Primary outcomes

the correlation between presence of cemento osseous dysplasia and gender/ age

Time frame: for three months from the beginning of the study

It usually affects female and black patients. Most of the patients are initially diagnosed between the ages of 30 and 50, and the diagnosis is almost never made in individuals younger than 20
cemento osseous dysplasia lesion's location and relationship with the anatomical structures

Time frame: for three months from the beginning of the study

If the lesions were in association with the teeth, the teeth numbers were recorded. The periphery of the lesions was divided into two sections: well-defined (corticated, sclerotic, non-corticated and partially corticated) and ill-defined (perforating, diffuse and invasive). The shape of the lesion was classified as circular, oval or irregular. The presence of a hypodense capsule was assessed as present, absent or partially present. The involvement with the adjacent structures - cortical bone (lingual and buccal), mandibular canal, mental foramen, nasopalatinal canal, incisive foramen, maxillary sinus, nasal fossa and anterior mandibular canal - was assessed and recorded. The effects on the cortical bone were assessed as intact, thinning, expansion and thinning, thinning and perforation, expansion, thinning and perforation or perforation. The internal calcified parts of the lesions.
cemento osseous dysplasia lesions dimensional measurement of the lesions

Time frame: for three months from the beginning of the study

The internal calcified parts of the lesions and the total volume of the lesions were also assessed.

The greatest linear dimension of the buccolingual, buccopalatinal and mesiodistal positions was measured on the axial plane, while the supero-inferior dimension was measured on sagittal or cross-sectional images.
cemento osseous dysplasia lesions volume of the lesions

Time frame: for three months from the beginning of the study

The internal calcified parts of the lesions and the total volume of the lesions were also assessed.

Sponsors and collaborators

Lead sponsor

Recep Tayyip Erdogan University Training and Research Hospital

Other

Registry information

Official study title

A Retrospective Radiological Analysis of Cemento-Osseous Dysplasia Using 3D Imaging

Important dates

Study start: 2019
Primary completion: 2020
Study completion: 2020
First posted: Oct 29, 2020
Registry last updated: Oct 29, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed