Skip to main content
OpenTrials
Completed

NCT Number: NCT01227083

2nd_Computerized Asthma Specific Quality of Life(cAQOL)

Comparison of the responsiveness of two different asthma-specific QOL measures (AQLQ and cAQOL) in Korean patients with persistent asthma

Completed

Looking for future studies?

Notify Me

Key information

Age range

20 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Ajou University Medical Center

Suwon, 443-721, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient aged 20-70 years
  • Patient diagnosed with asthma over six months ago
  • Asthma diagnosis
  • Airway reversibility, FEV1 ≥ 12% and 200mL or
  • Airway hyper-responsiveness, PC20 < 16 mg/mL or
  • More than two weeks, more than 2 times a day in excess of 20% PEFR diurnal variability patient
  • FEV1 55-100% of predicted value patient
  • Inhaled corticosteroids alone or inhaled corticosteroids and beta agonists used patient
  • Currently, at least if you have one or more asthma symptoms, asthma control test (ACT • Asthma Control Test) score of less than 19 characters
  • Patients who sufficiently listen to the purpose and content of this trial and the properties of investigational products and voluntarily agree with the participation to sign a written consent approved by IRB of Ajou University Medical Center before the participation in this trial

Exclusion criteria

  • Current smoking or smoking in the past 15packyears
  • Patients who show a symptom of an acute disease within 14 days before the beginning of this trial (administration of trial medication)
  • Recent changes in asthma treatment for 28days
  • Chronic diseases that affect the quality of life

Treatment and study plan

Primary outcomes

  1. Two asthma quality of life measurement tool

    Time frame: 24 weeks treatment

    Two asthma quality of life measurement tool (cAQOL, AQLQ) and the correlation between ACT

Secondary outcomes

  1. Correlation between cAQOL/AQLQ

    Time frame: treatment screening, week1,week12,week24

    -Correlation between cAQOL/AQLQ and other clinical parameters including FEV1, and asthma exacerbation.

  2. Association of asthma control therapy and a questionnaire

    Time frame: 24 weeks treatment

    -The proportion of subjects with achieving well controlled asthma within ACT & cAQOL-guided management strategy with ICS or ICS/LABA based on GINA 2006 guidelines during 24 weeks.

  3. asthma patient genotypes

    Time frame: Screening

    Sub-group of ADRB2 and NK2R genotypes

Sponsors and collaborators

Lead sponsor

Ajou University School of Medicine

Other

Collaborators

  • Dong-A University
  • Inha University Hospital
  • Yonsei University

Registry information

Official study title

Comparison of the Responsiveness of Two Different Asthma-specific QOL Measures (AQLQ and cAQOL) in Korean Patients With Persistent Asthma

Acronym: 2nd_cAQOL

Important dates

Study start
2010
Primary completion
2012
Study completion
2012
First posted
Oct 25, 2010
Registry last updated
Nov 13, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.